My sister does not want me in her life. What should I do?

You can choose your friends but not your relatives. Basically, you and this woman are strangers with just a remote blood tie. You didn't get much family life as kids so I suspect you in particular have a rather idealised picture of what family life should be like....everyone smiley and happy. Real life isn't like that at all. In the best of families there is always strife and in your broken family that strife manifests itself a bit more openly and violently. Your sister has issues. She doesn't think the same way as you. You have nothing much in common. You don't really like her - and why should you? She's a virtual stranger. She says she doesn't want you in her life any more. That's sad because you would obviously like her in yours in some form or other - but I think, in the cirstances, you should just let her go. Don't be too critical of her. She's a mixed up person (due to her childhood experiences) who takes it out on the people around her and you were an easy target because you needed her more than she needed you. Let her go. You don't need such a troublesome person in your life. You gave it your best shot and she didn't reciprocate so you have nothing to beat yourself up about. It's her loss as you sound like you'd have made a good brother to her. Let her go.